New research suggests certain parasites may be subtly tweaking our health and even our personalities

The parasite made me do it: How a common infection could manipulate our behavior

The parasite made me do it: How a common infection could manipulate our behavior

(Credit: pogonici, via Shutterstock)

This article was originally published by Scientific American.

Scientific AmericanImagine a world without fear. It might be empowering to go about your daily life uninhibited by everyday distresses. You could cross highways with confidence, take on all kinds of daredevilry and watch horror flicks without flinching. Yet consider the prospect a little more deeply, and the possibilities become darker, even deadly. Our fears, after all, can protect us.

The basic aversion that a mouse has for a cat, for instance, keeps the rodent out of death’s jaws. But unfortunately for mice everywhere, there is a second enemy with which to contend, one that may prevent them from experiencing that fear in the first place. A unicellular organism (a protozoan), Toxoplasma gondii, can override a rodent’s most basic survival instincts. The result is a rodent that does not race away from a cat but is instead strangely attracted to it.

Toxoplasma‘s reach extends far beyond the world of cat and mouse. It may have a special relationship with rodent and feline hosts, but this parasite also infects the brains of billions of animals on land, at sea and in the air. Humans are no exception. Worldwide, scientists estimate that as many as three billion people may be carrying Toxoplasma. In the U.S., there is a one-in-five chance that Toxoplasma parasites are lodged in your neural circuits, and infection rates are as high as 95 percent in other countries.

For most people, this infection appears asymptomatic, but recent evidence shows that Toxoplasma actively remodels the molecular landscape of mammalian brain cells. Now some researchers have begun to speculate that this tiny single-celled organism may be tweaking human health and personalities in stealthy, subtle ways.

What the cat dragged in

Researchers first discovered T. gondii in 1908, and by the end of the 20th century they had a good grasp on how people could pick up this parasite. The story starts with cats: for reasons that scientists have yet to unravel, Toxoplasma can sexually reproduce only in the feline gut. The parasite breeds within its feline host and is released from the feline’s tail end. Cats are such obsessive groomers that it is rarely found in their fur. Instead people can become infected from kitty litter or by ingesting it in contaminated water or food.



Within a new host the parasite begins dividing asexually and spreading throughout the host’s body. During this initial stage of the infection, Toxoplasma can cause the disease toxoplasmosis in immunocompromised or otherwise susceptible hosts, leading to extensive tissue damage. Pregnant women are particularly at risk. If a woman is infected with Toxoplasma for the first time during pregnancy, the parasite may invade the developing fetus, cutting through tissues and organs as it spreads from cell to cell. Infection early in pregnancy can result in miscarriage or birth defects.

In otherwise healthy individuals, however, the only symptoms during this period are brief, flulike discomforts such as chills, fever and body ache. Within days the immune system gets the parasite under control, and Toxoplasma retreats into a dormant state. It conceals itself within a hardened wall in the host’s cells, a structure called a tissue cyst.

This stage of the infection has no other discernible symptoms, but individuals with dormant infections who develop compromised immune systems—because of AIDS, an organ transplant or chemotherapy—may experience severe complications. With the body’s defense systems weakened, Toxoplasma can reactivate and grow uncontrollably.

Once infected, a person will remain a carrier for life. Our immune system is apparently incapable of eliminating the tissue cysts, nor can any known drug. Nevertheless, the infection, detectable with a blood test, has long been viewed as relatively benign. After all, many people carry this parasite with no obvious ill effects. Only recently have scientists begun reexamining this belief.

Eat me, Mr. Kitty

In the 1980s researchers noticed unusual behaviors in Toxoplasma-infected mice. The rodents became hyperactive and groomed less. In 1994 epidemiologist Joanne Webster, then at the University of Oxford, observed that rats harboring tissue cysts behaved differently from their uninfected counterparts. Instead of fleeing from cats, the infected rodents moved toward them—making them easier prey.

Webster suspected that this “fatal feline attraction,” as she called it, was a crafty way for the parasite to get back into a cat’s belly to complete the sexual stage of its life cycle. In the years to follow, this idea gained ground: a large body of work now shows that the parasite can indeed manipulate rodents’ behavior by altering neural activity and gene expression.

Several well-controlled experiments have shown that although uninfected rodents avoid areas that have been infused with cat stench, infected rodents do not seem to mind. Even more bizarre, in 2011 neuroendocrinologist Robert Sapolsky of Stanford University, molecular biologist Ajai Vyas of Nanyang Technological University in Singapore and their colleagues found that—at least in terms of neural activity—infected rats appeared to be sexually attracted to cat scent.

In the mammalian brain, the “defensive” and “reproductive” neuronal pathways run in parallel. These pathways start at the olfactory bulb, involved in odor detection, and ter-minate at the limbic system, an area critical to basic reactions such as fear and arousal. Their proximity may partially explain how the parasite manipulates rodent behavior.

Working with 18 infected and 18 uninfected male rats, Sapolsky and his colleagues studied the rodents’ behavior when they were exposed to either the odor of female rats or cat urine. Then they sacrificed the animals and looked at their brains. The researchers found a slight enrichment of parasite cysts in the limbic system compared with other brain areas.

They also assessed which parts of the brain had been operating during exposure to odors by staining the cells with a solution that revealed c-Fos, a protein expressed when neurons are active. The Stanford researchers discovered that infected rodents had high levels of engagement in their brain’s reproductive pathway in response to the odor of both female rats and felines. In addition, the team found that infected rodents exposed to cat urine showed activation in the reproductive pathway similar to what uninfected rodents showed for the scent of a female rat. These results suggest that in infected rats, neural activity shifts from the defensive to the nearby reproductive pathway. Instead of smelling danger, the rats smell love.

Scientists are not sure how exactly the parasite elicits this fatal attraction, but one clue surfaced in 2014 in Vyas’s laboratory. Vyas and his colleagues showed that Toxoplasma increases its host’s levels of a neurotransmitter involved in social and sexual behavior. To accomplish this task, the parasite alters DNA methylation. Methylated genes are silent, blocked by a molecular cap. Toxoplasma uncaps a group of genes that spurs the creation of the sex-promoting neurotransmitter. Vyas and his team discovered this trick by performing the process in reverse: when they administered a chemical compound to the infected rats that silences the associated genes, the rats’ peculiar attraction to feline odor vanished.

Kiss and spit

With evidence mounting that Toxoplasma can influence its host’s brain, other scientists set out to understand the parasite’s effects at a much smaller scale: within each host cell. Their findings suggest that this microbe is particularly insidious—the changes it makes may be permanent.

To replicate, Toxoplasma must invade a cell. Stanford parasitologist John C. Boothroyd has dubbed this process “kiss and spit.” The parasite first attaches to the host cell (the kiss) and then releases an arsenal of foreign proteins into that cell (the spit). Toxoplasma then enters the host cell, and the injected proteins help it redecorate its new home.

The parasite’s first act is establishing a protective bubble in which it can divide in peace without attacks from host cell proteins. (Later, during the infection’s dormant stage, these bubbles thicken to become tissue cysts.) The parasite then moves the mitochondria, which serve as the cell’s powerhouses, to be adjacent to the protective bubble. It also acts on the cell’s DNA, inhibiting the expression of some host genes while activating others. Finally, Toxoplasma modifies host proteins to alter their function and inhibit the immune response.

Altogether, these modifications ensure that the host cell will live a long time and supply energy to the parasite, without alerting immune cells that a parasite has moved in. Although these findings have principally been made with rodents, work with human cell cultures suggests that the same changes probably take place in the human body. In our labs, we are studying how Toxoplasma replicates and interacts with its host in an effort to develop new drugs to treat this infection.

Remarkably, a study that Boothroyd’s group published in 2012 showed that Toxoplasma not only spits into the cells it invades but also spits into cells that it does not infect. This behavior—spitting proteins in passing without lingering in the cells—is a recent discovery in the microbial world. Consequently, cells that are not harboring Toxoplasma contain parasite proteins that can co-opt and reprogram that cell. In the brains of infected mice, cells that have been spat into but not invaded are even more common than ones containing parasites. This widespread scattering of proteins means Toxoplasma can affect its host at a global level, making it easier to imagine how the parasite might manipulate the activity of an entire animal.

In 2013 biologist Michael Eisen of the University of California, Berkeley, and his colleagues found that a rodent’s strange attraction to cat odors may be permanent, even if there are no longer signs of infection. In one study, Eisen exposed mice to a mutant strain of the parasite that does not appear to form brain cysts. Four months later the infected mice had no detectable parasites in the brain, yet they were still attracted to cat odors instead of repelled. This finding suggests that even if the parasite can be removed from the body, behavioral changes may persist. The infection leaves a mark, like a permanent parasite-given tattoo.

The human connection

The fact that people do not throw themselves into the lion cage at the zoo strongly argues that Toxoplasma does not affect humans in the way it transforms mice. Mammalian brains are not all the same, and Toxoplasma‘s tricks are most likely specially suited for rodents. The parasite has little to gain, in evolutionary terms, by adapting to control the human brain. We are, after all, a “dead-end” host—the parasites within us are unlikely to return to the cat gut for breeding. Nevertheless, these cysts lodged in our brains could be manipulating us in subtle, unexpected ways.

A large body of research, mostly conducted by parasitologist Jaroslav Flegr of Charles University in Prague, supports the idea that Toxoplasma harbors the potential to change human behavior. In a series of personality assessments spanning more than a decade and involving nearly 2,500 individuals, Flegr and his colleagues found that certain traits often coincide with a Toxoplasma infection. For example, infected men tend to be introverted, suspicious and rebellious, whereas infected women tend to be extraverted, trusting and obedient.

Using a simple reaction time test, Flegr has also found that infected individuals are slower to respond than uninfected peers. This lag may relate to another correlation he has identified. In a 2009 analysis of 3,890 military conscripts in the Czech Republic, those with latent toxoplasmosis who also had a negative blood type, meaning they lacked the protein RhD, were six times more likely to be in a fender bender than those who were Toxoplasma-free or who had a positive blood type. The function of RhD is unknown. Flegr’s results suggest RhD somehow protects people against Toxoplasma‘s effects, but how it does so remains a mystery.

More recently, Flegr and his colleagues found that some of the changes that occur in mice also exist in humans—albeit in a gender-specific manner. In 2011 the researchers asked 34 Toxoplasma-infected students and 134 noninfected students to rate the intensity and pleasantness of urine samples from different animals. Curiously, infected men found cat urine odor more pleasant than uninfected men; in women, the opposite occurred.

Another line of research has focused on a potential link between toxoplasmosis and schizophrenia. In 2001 psychiatrist E. Fuller Torrey of the Stanley Medical Research Institute and neurovirologist Robert Yolken of the Johns Hopkins University School of Medicine reported significantly more antibodies associated with Toxoplasma in patients experiencing their first schizophrenic episode as compared with healthy peers. Although this initial study was limited to only 38 people, additional studies in the ensuing years have largely supported this link.

Fascinating and attention-grabbing as these studies may be, they come with several caveats. The sample sizes are relatively small, meaning the findings are preliminary. They do not definitively demonstrate that Toxoplasma causes behavior changes in humans. In the case of schizophrenia, it is important to note that the condition is complex and may involve many triggers. The parasite may be one contributor, but it is also possible that people with schizophrenia may simply behave in ways that make them more likely to pick up an infection. No hard evidence has emerged to date that directly implicates the parasite as a cause for any psychosis, including schizophrenia.

Ultimately these provocative findings probably reflect a complex exchange among various factors. Certain genetic predispositions, for example, or even an interaction between Toxoplasma and another infectious agent could mean that some people are more susceptible to the parasite’s persuasion. Only larger studies from multiple research groups will determine precisely what this parasite may do to the people it infects.

An accidental meddler

As researchers continue to uncover the astonishing effects that Toxoplasma has kept secret for so long, many scientists are beginning to think that Toxoplasma‘s impressive cellular and molecular tricks make it capable of causing disruptions in a human host. At the very least, the findings from human surveys beg for further clarification.

If you are curious whether you carry the parasite, you can get a blood test. In the meantime, you can increase your odds of staying Toxoplasma-free by maintaining good hygiene for you and your feline friends. If cats wander through your yard, the Centers for Disease Control and Prevention recommends wearing gloves and a mask when gardening and keeping any sandboxes closed up when not in use. Other basic health tips—cleaning fruits and vegetables, thoroughly cooking meats and washing hands regularly—are also important for avoiding an infection.

The notion that Toxoplasma could radically reorient the brain and behavior is certainly disturbing. But perhaps these findings are a reminder of a more basic truth. Each person is actually a rich ecosystem. For every human cell in the body, there are 10 more bacterial cells that influence physiology, metabolism and health. The protozoan Toxoplasma is just another stowaway within the system and one that warrants further study. After all, we will never fully understand ourselves without learning about our microbial companions.

http://www.salon.com/2015/03/27/the_parasite_made_me_do_it_how_a_common_infection_could_manipulate_our_behavior_partner/?source=newsletter

 

US House passes sweeping new bipartisan assault on Medicare

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By Kate Randall
27 March 2015

In a 392-37 vote, the US House on Thursday approved a bill that makes sweeping changes to the Medicare program that provides health insurance to more than 54 million seniors and the disabled. The Medicare Access and CHIP Reauthorization Act must be approved by the US Senate and signed into law by President Obama, who indicated his support for the measure earlier this week.

The bipartisan bill, drafted by Republican House Speaker John Boehner and Democratic Leader Nancy Pelosi, ties future payments to doctors for Medicare services to “quality of care,” shifting away from traditional fee-for-service payments. And for the first time, the universal Medicare program will institute means testing for higher-income seniors, requiring higher premiums for these individuals to access benefits.

The bill constitutes a historic attack on the Medicare program. Boehner called it the “first real entitlement reform in nearly two decades”—a reference to the assault on welfare launched under the Clinton administration in 1996. “Today is about a problem much bigger than any doc-fix or deadline. It’s about solving our spending problem,” he said.

Pelosi echoed Boehner’s comments, declaring that it had been a “privilege” to work with the House leader, and that she hoped the agreement “will be a model of things to come.”

The coming together of the Republican and Democratic Party leadership behind the overhaul exposes the unanimity within the ruling class on the need for sharp cuts in “entitlement” programs—Medicare, Medicaid and Social Security.

It provides a permanent “fix” to a 1997 law that tied doctors’ Medicare fees to overall economic growth. As overall health care costs have risen sharply, that formula threatened deep reimbursement cuts to doctors, cuts that Congress has blocked with patchwork measures 17 times since 2002.

The House bill will do away with the scheduled payment cut, set to kick in April 1, and replace it with a 0.5 percent yearly raise in payments through 2019. After this, a new payment system based on “quality of care” will be implemented.

Such language has been adopted by Medicare in other frameworks, and is generally measured by readmission rates and similar statistics. In other words, doctors who see more of their patients readmitted will receive cuts in reimbursement. However, readmission is closely correlated with poverty and other social factors, thus cutting spending on health care in lower-income and working class areas.

By disconnecting reimbursements from services provided, doctors will also be incentivized to ration care and cut back on testing—the overarching aim of all the health care “reform” proposals backed by both Democrats and Republicans. The change will result in reduced services for Medicare patients overall and deep spending cuts by the government.

This shift has long been promoted in the private insurance sector. It is also a key goal of the Obama administration, which earlier this year set a goal to tie the vast majority of Medicare payments to programs promoting cost-cutting.

The second main feature of the bill would institute means testing for Medicare recipients, requiring higher-income seniors to pay more toward Medicare premiums for insurance and prescription drug coverage. Initial estimates are that this change would result in Medicare savings of around $30 billion over the next decade.

Congressional Republicans and Democrats alike are well aware that this fundamental change opens the floodgates for transforming a program that for the last half-century has provided health care insurance to those over the age of 65, regardless of income, into a poverty program available to only those poorest segments of society. This is seen as a first step in it being starved of funds and ultimately dismantled.

Boehner, salivating at these prospects, commented, “We know we’ve got more serious entitlement reform that’s needed. It shouldn’t take another two decades to do it.” He indicated that the Republicans would continue to push for funding cuts to other federal benefit programs.

Some Congressional Republicans balked at the overall cost of the measure, which the Congressional Budget Office estimates at $214 billion over the next decade. This would be paid for through $141 billion in new spending, with the balance divided between higher monthly premiums for higher-income Medicare recipients and payments by nursing homes and other health care providers.

Boehner and the Republicans see the implementation of means testing—and the subsequent savings for government—as a starting point for future overhauls to Medicare and other federal programs. This particularly applies to Social Security, the universal retirement program enacted in 1935 in the wake of the Great Depression.

Both Medicare and Social Security are not “gifts” by the government, but benefits based on the funds workers pay into these programs for their entire working lives through deductions from their paychecks.

As window dressing, the bill also provides two more years of funding to the Children’s Health Insurance Program (CHIP), which serves 8 million low-income children, as well as to the nation’s 1,200 community health centers. While Pelosi and the White House had pushed for four-year extensions for both of these programs, the majority of Congressional Democrats willingly compromised on this issue in order to push through the changes to Medicare.

The bill also includes abortion funding restrictions at community health centers, incorporating components of the so-called Hyde Amendment, which forbids federal funding of abortion except in the cases of rape, incest, or the endangered life of the mother.

Leaders of the House “pro-choice” caucus assured skeptical Senate Democrats that the bill’s language provides no additional abortion restrictions beyond those that already apply. In fact, the Obama administration acceded to these reactionary and unconstitutional restrictions in language in the Affordable Care Act (ACA).

Speaking Wednesday on the occasion of the fifth anniversary of his signing into law of what is popularly known as Obamacare, the president indicated his support for the new bipartisan Medicare bill. “I’ve got my pen ready to sign a good bipartisan bill,” he said.

The coinciding of the ACA’s anniversary and the current bipartisan bill is noteworthy. From the start, Obama’s health care overhaul has been aimed at a fundamental restructuring of the health care system, aimed at lowering costs for the government and corporations while slashing health care services for the vast majority of Americans.

Taking its cue from Obamacare, the change in Medicare represented by Pelosi and Boehner’s bill will set an example that can rapidly be extended throughout the health care system. Despite many Congressional Republicans’ vocal opposition to the ACA and vows to see it repealed, they are in agreement with its aim of rationing care and funneling more money to the health care industry.

Although the bill faces some opposition in the Senate, it is expected to pass, either before Congress leaves for spring recess today or on its return in two weeks. If it does not pass before the recess, Congress will likely pass a temporary fix to the Medicare payments to doctors.

 

http://www.wsws.org/en/articles/2015/03/27/medi-m27.html

The California drought: Water-rationing plan leaves corporate interests untouched

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26 March 2015

The unprecedented drought gripping California has deepened for the fourth consecutive year, having already set new records for the lowest annual precipitation levels on record. 2014 brought the highest calendar-year temperature for the state, while this February was the hottest on record and this January the driest.

A recent study conducted by Daniel Griffin and Kevin J. Anchukaitis found that the current episode “is the most severe drought in the last 1200 years, with single year (2014) and accumulated moisture deficits worse than any previous continuous span of dry years.”

Last Thursday, California Governor Jerry Brown announced a new bill, which he claims will provide $1 billion in drought-related spending, mostly on flood protection. The bill merely expedites funds already approved by California voters, and will do nothing to resolve the state’s dire water crisis.

Last Tuesday, the California State Water Resources Control Board intensified emergency legislation targeting residential “water wasters,” initially implemented last summer. The law imposes a $500 fine for offenses including excessive lawn watering.

Both measures leave untouched the giant agribusinesses and oil corporations that account for a majority of the state’s water usage and dominate the political system.

On Sunday, Chuck Todd, host of NBC’s Meet the Press, asked Governor Brown whether “considering how much water…is used for fracking [hydraulic fracturing]…isn’t that alone enough reason to prohibit fracking or temporarily stop it?”

Brown sought to deflect the question, responding: “No, not at all. First of all, fracking in California has been going on for more than 50 years. It uses a fraction of the water of fracking on the East Coast for gas, particularly.”

Throughout his entire political career, dating back to the 1970s, Brown has been entirely beholden to Big Oil, while posturing as a defender of the environment. He has accepted at least $2 million in campaign contributions from oil corporations since 2006, including Chevron, Occidental Petroleum, Southern California Edison, Valero Energy, Tesoro Corp, Conoco Phillips and Aera Energy (owned jointly by Shell and ExxonMobil). Most of these companies donated the maximum amount possible to Brown’s reelection campaign last November.

Earlier this year, the San Francisco Chronicle reported that, for years, state regulators knowingly allowed oil companies, mostly in the impoverished Central Valley, to pump their wastewater into groundwater aquifers that contained drinkable water.

Every year, the oil industry in California produces roughly 130 billion gallons of wastewater, as the state is the third-largest oil producer in the US. Kern County, home to most of California’s oil and hydraulic fracturing (fracking) wells, has the worst air quality of any county in the US, along with some of the highest rates of cancer and respiratory illness.

Climate change, a byproduct of the oil corporations’ unrelenting drive to accumulate profit, has played the most significant role in determining the length and severity of the ongoing drought, as well as the likelihood for future droughts.

On March 12, the leading bourgeois press outlet in the state, the Los Angeles Times, prominently featured an op-ed penned by NASA’s senior water scientist, Jay Famiglietti, titled “California has about one year of water left. Will you ration now?”

Famiglietti begins the op-ed by stating that “Right now the state has only about one year of water supply left in its reservoirs, and our strategic backup supply, groundwater, is rapidly disappearing.” He proposes a water rationing scheme across “all of the state’s water sectors, from domestic and municipal through agricultural and industrial.”

Despite the calls by experts to place restrictions on business, last Tuesday the State Water Resources Control Board furthered emergency drought regulations that target solely consumers, leaving agribusiness untouched. Local water districts must restrict lawn watering to twice weekly, among other tepid reductions in consumers’ water usage.

The state will now place local water agencies under intense scrutiny, ensuring that they levy $500 daily fines against “water wasters” that were first enacted last summer. Over the past year, few fines were doled out locally, with one notable exception being Santa Cruz, which issued over $1.6 million in penalties against individual consumers. The cities of San Ramon and Dublin, both east of Oakland, issued $40,000 in combined fines.

Instead of adopting any sort of progressive policy to implement well-known, rational planning methods that would ensure the viability of California’s water supply for future generations, the existing political setup seeks to reduce the highly complex issue to merely punishing individual consumers.

The drought has already devastated thousands of working-class families, as an estimated 17,100 agricultural laborers lost their jobs during last year’s growing season alone, with that number expected to rise significantly this year. The brunt of these job losses occurred in the agricultural heart of the state, the Central Valley, a stretch of land roughly 450 miles long, from Bakersfield in the south to Redding in the north, and between the Sierra Nevada to the east and the Coast Ranges to the west.

Between the spring of 2013 and the spring of 2014, water levels in groundwater basins throughout the Central Valley fell by 50 feet or more, amid a race to drill ever-deeper and more expensive groundwater pumps. In one of the Central Valley’s most productive agricultural regions, Tulare County, 874 well permits were issued in the first six months of 2014 alone, 44 more than the county issued in all of 2013.

In the process, hundreds of private wells across Tulare County dried up, leaving thousands of East Porterville’s working-class residents without water. The state’s only response to this dire crisis has been to provide limited amounts of bottled water to inhabitants, with no plans implemented to develop water infrastructure for residents.

A package of three bills signed last September by Brown will implement the first-ever groundwater regulations in the state, but will have no effect until 2040, and even then will not require businesses to report how much water they pump individually. Barring an end to the drought, which scientists have noted could become a decades-long “megadrought,” all remaining groundwater will have long disappeared by that time.

The legislation passed last Tuesday does nothing to curb groundwater usage by the agricultural giants, the only ones capable of shelling out upwards of $400,000 to drill the 2,000-foot (600-meter) pumps required to extract dwindling groundwater reserves.

Agriculture accounts for roughly 80 percent of California’s total water usage, while the remainder is used by urban industry and household consumers, with outdoor landscaping accounting for roughly half of total urban usage. Thus, at most the recent regulations will cause a 5 percent reduction in the state’s total water usage.

California produces over 99 percent of all almonds, pistachios, olives, walnuts, rice, plums, dates, figs, raisins, artichokes, kiwis, peaches and pomegranates grown in the US, and is also the leading producer of dozens of other food commodities. In recent decades, international demand has led to a large transition toward growing orchard and vineyard crops.

During the drought, many farmers have fallowed even more of their traditional vegetable crops, diverting water toward almond trees and other orchards, which take longer to mature and are thus a larger capital investment. California currently grows roughly 80 percent of the world’s almond supply, in addition to 43 percent of all pistachios and 28 percent of all walnuts, and these cash crops are indispensable to maintaining profitability.

The “almond empire” is centered in the San Joaquin Valley, home to the largest almond-growing monopoly in the world, Paramount Farming. Paramount’s owners, Stewart and Lynda Resnick, are closely connected to Governor Brown, as well as Democratic Senator Dianne Feinstein and other state politicians, and have influenced water policy in the state for decades.

This couple is the modern-day reincarnation of the most corrupt aspects of former Los Angeles Mayor Frederick Eaton and his associate Joseph Lippincott, immortalized in the character of Noah Cross, played by John Huston in the 1974 Roman Polanski classic Chinatown. In addition to Paramount Farming, their holding company also owns Paramount Citrus and Paramount Farms, the world’s largest growers of citrus and pistachios.

Financial interests, including New York-based retirement and investment fund TIAA-CREF and Hancock Agricultural Investment Group, a subsidiary of the insurance and financial services giant Manulife Financial, have recently joined the bumper crop frenzy, becoming some of the largest nut growers in California.

Despite the proven efficiency of drip irrigation for orchard and vineyard crops, 20.3 percent of all vineyard and 13.4 percent of all almond and pistachio crops in the state continue to be grown using flood irrigation methods. Thus, almond trees alone presently account for 10 percent of California’s total annual water usage, more than the combined domestic usage of the state’s 38.8 million inhabitants.

There are immense efficiencies to be gained through the statewide adoption of crop-specific irrigation methods and other efficiency improvements. Yet any such rational reorganization is blocked by the interests of the US financial oligarchy, which, controlling the entire political system, will not abide any impingement on its profits.

 

http://www.wsws.org/en/articles/2015/03/26/cali-m26.html

“BOYHOOD” THE MOVIE

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I watched “Boyhood” last night. Didn’t think I could deal with a film running nearly three hours focused on the reality-based coming of age theme. I was, however, much impressed by the epic technical achievement the film represents, and I was deeply moved by the genuinely human intimacies shared throughout. The ending was a powerful insight into the human condition.

Got me to thinking about the values of the tech-fueled Bay Area where I live.

I really loath, truly hate, the materialistic, money-fueled tech culture that has enveloped San Francisco. And it’s not the technology per se. I’ve been using and building computers since 1985. It’s the disgusting excess and glorification of same.

Interestingly, watching “Boyhood” last night reminded me that there are other, more appealing, lifestyles and choices still available in the country. The main character in the film was not obsessed with tech. He questions the value of the ubiquitous smart phone. He works after school. Middle class. He doesn’t dream of going to Stanford or MIT, etc., to get a degree in CS and code. Hell, he wants to be an artist. He’s interested in the meaning of life. Like people I used to know in school and throughout my life. He represents my American Dream. Not this SF version with conspicuous consumption and phony hipster culture.